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(Moderate) Propranolol is significantly metabolized by CYP2D6 isoenzymes? If "half-life" is 5 hours, when will I be able to "pass" a doping test.

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However, a 3-fold increase in plasma exposure to tacrolimus in a renal transplant patient (CYP3A5 non-expresser) upon initiation of amlodipine for the treatment of post-transplant hypertension resulting in reduction of tacrolimus dose has been reported?

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